Tags :Simulations Plus DDDPlus 5.0

Simulations Plus DDDPlus 5.0 Reimagine the in vitro dissolution experiment… Today, dissolution studies are the most frequently used tools in the development, characterization, and utilization process of pharmaceutical dosage forms, both immediate and controlled-release. As a formulation or CMC scientist, you’re often tasked with designing a product which achieves a target in vitro dissolution rate that will, hopefully, lead to desired in vivo exposure levels. Or, the lifecycle management team wants to assess the possibility of creating a once-a-day formulation which is bioequivalent to a B.I.D. (twice a day) or T.I.D. (three times a day) dosing regimen. You don’t have a lot of time or material available, so you begin manufacturing small lots of products to test under different conditions,...